Lopside is a Barkonaut, a specially trained dog who assists human astronauts on missions in space. He and the crew aboard the spaceship Laika are en route to set up an outpost on a distant planet.

When the mission takes a disastrous turn, the Barkonauts on board suddenly find themselves completely alone on their severely damaged ship.

Survival seems impossible. But these dogs are Barkonauts—and Barkonauts always complete their mission.