Ramona Quimby can't wait to start fourth grade. With a new baby sister to brag about, new calluses to show off, and a new best friend to get to know, everything's going to be great!

Or is it? When Ramona's spelling is atrocious, her teacher, Mrs. Meacham, is firm about her needing to improve. Then a scary incident at a friend's house leaves Ramona feeling at fault. Who knew growing up could be filled with such complicated situations?